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Cytomegalovirus Infection Minimally Affects the Frequencies of B-Cell Phenotypes in Peripheral Blood of Younger and Older Adults.

If I'm understanding the abstract correctly, here the authors report that B-cells are *not* changed with aging or with CMV status. I infer that they may have tested T-cell compartment as well ("However, in marked contrast to the T-cell compartment..."), which they might have observed to change with aging and/or CMV. They may have been referring to other publications in that statement. I did not find the full-text to see their results about the T-cell compartment (or whether they measured this at all).
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Effect of age and latent CMV infection on CD8+ CD56+ T cells (NKT-like) frequency and functionality.

This report suggests that CMV infection may enhance immune function in response to non-CMV pathogens (in this case: Staphylococcal Enterotoxin B). I suspect the effect of CMV and aging on NKT-like cells may be of interest in characterizing changes in immune parameters with CMV infection and aging, though I find it difficult to see how this report is helpful by itself for damage-cleanup efforts.
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Cytomegalovirus viral load within blood increases markedly in healthy people over the age of 70 years.

I tagged this paper with "Thymus" because I wonder whether this apparent age-related failure to control CMV might be related to thymic involution, and the related decline in cell-mediated immunity. Moreover, this report may complicate simple classification of "CMV-seropositive" and "CMV-seronegative", if, as the authors say, "CMV is extremely difficult to detect in healthy donors"; this complication of classification may confound many studies about CMV in aging and immune senescence.
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CMV seropositivity and T-cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ study.

I actually retained this one not for the association between CMV and CHD (though maybe there's something there to pay attention to), but for the immunity-characterization of the CMV+ group, for which the researchers measured CD4/CD8 ratio, senescence-like CD4 and CD8 memory cells. The nearly 10-fold difference in senescence-like CD4 memory cells in the CMV group, I find remarkable. They also report that low, senescent-like CD4 T-cells and CD27-/CD8+ T-cells were predictive of lower cardiovascular death.
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