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The Macrophage ‘Do not eat me’ signal, CD47, is a clinically validated cancer immunotherapy target.


Maximus Peto’s Commentary

See abstract (compiled by me).


The Macrophage ‘Do not eat me’ signal, CD47, is a clinically validated cancer immunotherapy target.
Ann Oncol. 2019 Mar 1;30(3):486-489.
Takimoto CH, Chao MP, Gibbs C, McCamish MA, Liu J, Chen JY, Majeti R, Weissman IL
DOI: 10.1093/annonc/mdz006
PubMed publication date (edat): 1/29/2019

Abstract

[Max Peto]: This paper had no abstract in PubMed, but it has a free full-text. I scanned the full-text, and it appears to be a mini-review of CD47 immunotherapy for cancer, including some clinical trial results of this strategy. I’m not sure whether this would be considered a “SENSible” approach to cancer; cleaning up the cancer once it’s started seems so, but that makes curing cancer sound simple, doesn’t it?

PMID: 30689700
Free Full-Text: https://www.annalsofoncology.org/article/S0923-7534(19)31086-5/fulltext

Maximus Peto

Max Peto is a longevity researcher and founder of Long Life Labs. A biochemist by training, he studies the biochemistry of aging and longevity and has worked with research organizations such as SENS Research Foundation, Methuselah Foundation, BioAge Labs, Life Extension Foundation, and Ichor Therapeutics. His work at Long Life Labs is focused on empowering people to understand and manage the most critical factors for better health and longer life.

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